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Thailand announced Thursday a breakthrough in the development of an AIDS vaccine. That came as scientists discovered the first-ever AIDS vaccine that has preventive efficacy. The vaccine has 31.2 percent efficacy in reducing the risk of HIV infection.
The following is a brief review of the arduous AIDS vaccine development path.
After AIDS first drew public notice in 1981, researchers in different countries, before the latest development, had fought a losing battle in developing a vaccine.
During the anti-AIDS campaign, researchers successively developed a variety of anti-AIDS medicines. However, the drugs can’t eradicate the HIV virus, which causes AIDS and has produced a series of variations.
An AIDS vaccine that can prevent HIV infection, therefore, has been regarded as the best weapon to deal with the deadly disease.
In 1997, then US President Bill Clinton said his country planned to develop an effective AIDS vaccine in the coming 8 to 10 years. The United States since has been zealous in developing a vaccine. Scores of vaccines underwent clinical trials but little substantial progress has been made.
Many researchers began to take pessimistic stands on whether an AIDS vaccine could be discovered. Some even thought efforts to develop a vaccine would come to a dead end.
David Baltimore, a Nobel laureate and famed AIDS researcher, pessimistically predicted that mankind can’t invent an AIDS vaccine within the next 25 years, if ever, because of the virus’ complex variability.
The latest progress in the race to find an AIDS vaccine received much applause around the world.
“Today marks a historic milestone,” said Mitchell Warren, executive director of the AIDS Vaccine Advocacy Coalition, an international group focused on developing a vaccine.
“It will take time and resources to fully analyze and understand the data, but there is little doubt that this finding will energize and redirect the AIDS vaccine field,” he said in a statement.

The Ministry of Health (MOH) on Thursday ordered all administrative and medical departmentsto ensure accurate reporting of A(H1N1) influenza cases, in response to a medical expert’s query over false reports. Zhong Nanshan, a medical expert in Guangdong Province, was quoted by on Thursday’s Southern Metropolis Daily as saying that he did not believe there had been only 53 deaths of A(H1N1) flu nationwide.
Zhong, an academician of the Chinese Academy of Engineering, said that some areas had left dead patients undiagnosed in order to conceal the real number of deaths from the flu.
Zhong said that “some areas have not been testing deaths from severe (pneumonia) and treating them as cases of ordinary pneumonia without a question,” the paper reported. Deng Haihua, spokesman of the MOH, said late on Thursday that the ministry welcomed supervision from all walks of society, including the media.
Deng said that the ministry had dispatched a total of nine teams to 12 provinces and autonomous regions to oversee prevention and treatment of the flu, especially treatment of severe cases.
He also promised that the ministry would continue to supervise local work and release information quickly. The ministry said on its website Wednesday, saying that it would start to update A(H1N1) flu information only once a week. Previously, it offered updates three times a week.
As of Sunday, almost 70,000 A(H1N1) flu cases had been reported on the mainland, with 53 deaths in total, according to the ministry.
Of all the flu cases reported last week, almost 90 percent were A(H1N1) cases, totaling
more than 10,000. So far, about 18.2 million people nationwide had been vaccinated, it said.
The ministry has advised the public to keep warm, to wash hands frequently and keep rooms ventilated daily.

The World Health Organization (WHO) said on Friday that it was assessing the public health significance of a mutation of the pandemic H1N1 virus detected in Norway and some other countries.
The Norwegian Institute of Public Health has informed the WHO of a mutation of the H1N1 flu virus detected in two patients who died and one with severe illness.
In addition to Norway, the mutation has also been observed in Brazil, China, Japan, Mexico, Ukraine and the United States, with the earliest detection occurring in April, the UN agency said in a statement.
“The significance of the mutation is being assessed by scientists in the WHO network of influenza laboratories,” the statement said.
“Although further investigation is underway, no evidence currently suggests that these mutations are leading to an unusual increase in the number of H1N1 infections or a greater number of severe or fatal cases,” it added.
According to the agency, the virus with this mutation remains sensitive to the antiviral drugs, oseltamivir and zanamivir, and studies show that currently available pandemic vaccines confer protection.
In addition, the mutations appear to occur sporadically and spontaneously. To date, no links between the small number of patients infected with the mutated virus have been found and the mutation does not appear to spread.
In a separate statement, the WHO said that the pandemic virus has thus far caused at least 6,770 deaths worldwide, of which more than 4,800 occurred in the Americas.

Hong Kong’s Department of Health said Monday that it previously detected a mutated form of the A(H1N1) flu virus using samples from a 1-year-old boy, which is the same mutation recently discovered in Norway.
The boy was infected in July and he has since recovered, much earlier than patients in Norway.
He was admitted to Prince of Wales Hospital on July 25 and had no travel history.
The virus was detected in one of the 123 genetic sequences the department studied.
“No evidence suggests that the mutation would cause an increase in the number of A(H1N1) cases. The mutated virus is sensitive to antiviral drugs Relenza and Tamiflu,”said a spokesman in the department.
According to the World Health Organization (WHO), the same mutated (changed) virus has been found in other countries and regions including the Chinese mainland, Brazil, Japan, Mexico and the United States.
The mainland confirmed more A(H1N1) cases.
All influenza cases were confirmed as A(H1N1) in the past two weeks in Shenzhen, Guangdong Province, Shenzhen TV reported Tuesday.

The World Health Organisation (WHO) issued new advice on the treatment of HIV Monday, the eve of World AIDS day, saying drugs should be given earlier and even be prescribed to breastfeeding mothers.
The WHO says that adults and adolescents should receive anti-retroviral therapy (ART) when their immune system strength falls below 350 cells per cubic millimeter of blood. In 2006, the WHO had set the level at 200 cells per cubic millimeter.
“These new recommendations are based on the most up-to-date available data,” said Hiroki Nakatani, assistant director-general for HIV/ AIDS, TB, Malaria and Neglected Tropical Diseases at the WHO. “Their widespread adoption will enable many more people in high-burden areas to live longer and healthier lives.”
The WHO also recommended that pregnant women exposed to the virus be treated with anti-retroviral drugs (ARVs) starting during the 14th week of pregnancy, and that treatment could continue during breastfeeding.
“Several clinical trials have shown the efficacy of ARVs in preventing transmission to the infant while breastfeeding,” a WHO statement said.
The WHO also said Stavudine, a relatively cheap HIV/AIDS drug that is widely used in developing countries, should be replaced with Zidovudine and Tenofovir, as they have less harmful side effects.

People in Gansu Province who have the HIV virus must inform their sexual partners within a month after they learn of the diagnosis, or risk criminal punishment, according to a new rule issued by the provincial health department.
The new rule was met with reservations from members of some AIDS support groups.
“The measure lacks human care because it’s too high a price for HIV carriers to inform others in China where discrimination on AIDS often leads to the collapse of whole families,” Mu Rongfeng, the leading member of Ai Zhi Guang (light of love) care group for HIV carriers, told the Global Times Wednesday.
“What they need is sympathy and help instead of administrative orders,” Mu said.
The rule stipulates that HIV carriers should also ask their partners to get a medical test, China Youth Daily reported.
Carriers who failed to do so would be regarded as intentionally spreading the virus.
They might be held responsible for civil compensation and even subject to criminal liability.
The provincial health authority said 41.89 percent of AIDS patients in the province contracted the disease through sexual contact.
Liu Wei, a legal advisor of the Aizhixing Institute of Health Education, suggested that both parties in a sexual relationship are responsible to prevent the spread of HIV.
“It’s unfair to put the burden of criminal responsibility on the carriers. Some may feel reluctant to go for HIV tests under huge social pressure,” he told the Global Times.
Wang Taixian, an administrative law expert of Southwest University of Political Science and Law, said legal channels, recognition from other community members and love should be used collectively to tackle the spread of AIDS.

China’s Ministry of Health said Tuesday that four deaths had been reported after inoculated with China-made A(H1N1) flu vaccine and three had been confirmed irrelevant to the vaccines.
The three deaths were “coincidental” and causes of the other death are yet to be finalized, Liang Wannian, director of the ministry’s emergency response office, said at a press conference.
Of the 26.18 million people nationwide who had been vaccinated by Monday, 2,867 suspected adverse reactions had been reported, Liang said. About four fifths of the reactions were fever or swelling.
“Clinical tests and practices in China and other countries have shown the A(H1N1) flu vaccines are safe,” Liang said.
As of Sunday, the Chinese mainland had reported 178 deaths from the flu. More than 90,000 people were infected and nearly 80 percent had recovered.
Liang warned that the flu situation in China was still “severe” with an increasing number of deaths and more counties and municipalities reporting confirmed cases.
The proportion of A(H1N1) flu also increased greatly to about 90percent of all flu cases in the past weeks.
Liang said schools were still the main venue for prevention.

While it is possible to get to Datong, Shanxi Province by train, we chose to drive. It is a three-hour-plus trip from Beijing and somewhat precarious due to the countless number of trucks driving according to their own traffic rules along the way.
Datong itself was nothing much of interest to us. It is an industrial city covered in coal dust. It is however, the starting point for most of the tours to the wonderful Yungang Caves and Hengshan Hanging Monastery.
From Datong you can either book a tour with a travel company or venture out yourself – finding the place is not too difficult, espe-cially if you speak Chinese.
Yungang Caves, or Yungang Grottoes, is a UNESCO world heritage listed site and is considered one of the most outstanding examples of ancient Chinese sculpture. All together the site is composed of 53 grottoes with 1,000 small niches holding more than 51,000 Buddha statues from very large to very small.
The grottoes were mainly constructed from 460-525 during the Northern Wei Dynasty (386- 534) under imperial and in later periods, private patronage.